Hyaluronic Acid – The Anti-Ageing Nutrient?


Hyaluronic acid, also known as hyaluronan or hyaluronate, is now widely available in capsules, serums, moisturisers and even injectables. But, is it the magical ingredient that appears to be on every skin manufacturers list and on every practitioner’s list of must have supplements?

What is Hyaluronic Acid?

Hyaluronic acid (HA) is a gel-like water holding molecule that is the space filler and cushioning agent in all mammals. HA cushions joints, nerves, hydrates skin and hair, and fills the eye. Although originally discovered in 1934 by Karl Meyer, HA gained momentum only after a visit by a reporter to a Japanese village of Yuzuri Hara to find out why both men and women in their 80’s and 90’s had smooth wrinkle free skin, flexible joints, full heads of hair and activity levels that defied their age. This was eventually found to be related to oestrogen-like molecules in their diet from soya and tofu, which sent signals to the cells to make more hyaluronic acid.

Our bodies roughly contain 15 grams of HA and it is found in virtually every part of the body. With such a widespread occurrence, it is logical that HA also has multiple functions. Scientific studies have shown that HA improves skin hydration, stimulates production of collagen in skin, works as an antioxidant and free radical scavenger, maintains skin elasticity, cushions joints and nerve tissues, has an antibacterial and anti-inflammatory activity and maintains the fluid in the eye tissues, which may help to protect against numerous possible eye concerns.

The average human body contains roughly 15 grams of HA, one third of which is degraded and synthesized on a daily basis. This is where the problems arise! The manufacture of every single protective agent in the body declines with age and HA is no exception to this rule. Decreasing levels of hyaluronic acid are known to accompany the ageing process and it is estimated that by the time we reach our mid-40’s, the synthesis of HA is roughly half that required by the body.

Benefits of Hyaluronic Acid

Skin: Almost half of the body’s HA is located in the collagen of skin and it is logical that HA plays a vital role here. Hyaluronic acid helps to retain over a 1000 times its weight in water within the cells of skin, making it an excellent moisturizer. In fact, no other biological substance can retain as much water as HA resulting in increased smoothness, softening and decreased wrinkles. Equally important is its ability to remove waste matter from cells including those where there is little blood circulation.

Today, hyaluronic acid is considered equally important, if not more important, than Collagen. The most common application for hyaluronic acid is in anti-ageing therapy, particularly with cosmetic procedures such as the elimination of skin imperfections and wrinkles, but these are not without problems and since HA is destroyed by the body, they need to be repeated regularly and are often expensive.

Joints: Most of us have heard of glucosamine supplements used for the treatment of arthritic conditions. Glucosamine belongs to a group of compounds known as glycosaminoglycans (GAGs). These compounds help you build stronger, healthier and more flexible joints. Hyaluronic acid is the most active form of GAG’s and it works as a shock absorber lubricating the fluid in the joint tissues as well as stabilising its breakdown. It also works to remove the waste products, often acidic in nature, that arise from the destruction of the cartilage matrix and hence eases joint pain. As an antioxidant, it further supports joint health by protecting joint destruction due to free radicals. Hyaluronic acid can be administered by way of injections directly into the knees, although treatment can be very expensive and often needs to be repeated due to its natural breakdown.

Eyes: Hyaluronic acid is found in the vitreous fluid in the eyes and gives them their shape and characteristics. The first hyaluronic acid medical product was intended for use in eye surgery specifically for cataract surgery and glaucoma and was used to hasten the healing process following surgery. Since hyaluronic acid lubricates the eye tissues, it is of great benefit for people suffering from dry eyes. Oral supplements of HA may also help your eyesight. The reason for this is that as we age, less HA is found in the eye tissues and it is required to help support the eye structures.

Gum Disease: Gum disease is a common problem in the UK affecting 3 out of 4 adults over the age of 35. Gum disease, and not tooth decay, is the single biggest cause of tooth loss. Hyaluronic acid is an important connective tissue component in the gums helping with the regeneration of fresh healthy gum tissue as well as reducing any inflammation that leads to bleeding gums. Several studies indicate that applying hyaluronic acid as a gel (Gengigel) helps to reduce gum disease and bleeding gums.

There are many additional benefits reported with the use of hyaluronic acid and these include faster wound healing, increased energy, dry skin relief, improved muscular strength and increased mental alertness. Can we really afford not to take hyaluronic acid supplements?

At the time of writing, there were no well-known drug interactions with the use of Hyaluronic Acid capsules.

This content is not intended to replace conventional medical treatment. Any suggestions made and all herbs listed are not intended to diagnose, treat, cure or prevent any disease, condition or symptom. Personal directions and use should be provided by a clinical herbalist or other qualified healthcare practitioner.

Shabir Daya | , , , , , , , , , , , ,
  • Kishlette

    Thanks for your response and I note the information on ceramides. I was actually asking about the use of oral HA supplements and whether a topical HA serum would also be needed/beneficial or redundant. I don’t have dry skin on my face so I don’t think I need both, but that was my question – it was about whether there’s any benefit to both oral and topical HA

  • http://www.victoriahealth.com/ Victoria Health

    I personally believe in the use of both topical hyaluronic acid, irrespective of whether you suffer from dry skin or not, as it keep skin hydrated. I suppose you could try leaving the serum out and see how your skin feels after three months.

  • Kishlette

    Thank you! That sounds like a reasonable option

  • Shelby Hall

    NIOD Multimolecular hyaluronic acid serum is amazing. I’m on my third bottle. I literally have a shopping alert for it anytime a sale comes up, I snatch it up. Also, the Hydration vaccine by NIOD too. Has helped to change my skin. I have just started adding HA supp to my morning smoothies. It really is a great ingredient, especially if you live in a humid area. I, however, live in Phoenix so the HA needs to have different molecular weights. The cheaper brands don’t and pull moisture from the air. If it can’t do that, it pulls from the deeper layers of the skin. That’s why NIOD is so great. It has a dozen or so different types of HA.

  • http://www.victoriahealth.com/ Victoria Health

    Thank you Shelby for sharing. NIOD’s MMHC is truly an outstanding product and there is not a hyaluronic acid serum on the market that can touch it!

  • Melissa Locks

    I’ve been using Hyaluronic Acid for a while. So far I am very pleased with the Lady Soma Renewal Serum (which contains hyaluronic acid) with it. No funky smell or stickiness. I have a combination skin type: dry and oily in t-zone area. My trick is to apply when my face is still wet when it feels really dry cause of the dry weather in California or apply right before.

    It helps my skin hydrated better this way without breaking-outs.

  • http://www.victoriahealth.com/ Victoria Health

    Thank you for your input Melissa however my recommendation would be to consider the use of The Ordinary Hyaluronic acid + B5 which is one of our best selling serums and you don’t have to pay a lot for it! Shabir

  • Francesca Micucci

    Hi, I’ve got a question.
    Is it possible to combine and use the HA high strenght with the Niods serum at the same time.
    thank you

  • http://www.victoriahealth.com/ Victoria Health

    Dear Francesca, You can definitely take high strength hyaluronic acid capsules and use NIOD serums including CAIS and MMHC2.
    Best wishes,

  • http://rozrr.deviantart.com/ Roz Rayner-Rix

    I have just purchased skin cream and tablets… When can I expect to see any benefits?

  • http://www.victoriahealth.com/ Victoria Health

    Hi Roz, I would expect to see benefits within four to six weeks.
    Best wishes,

  • iphrase

    Just started taking hylauronic acid and collagen orally for my osteoarthritic knees. It’s simply amazing, only been on it a week at half dose and am already walking up and downstairs without holding the banister. I’ve not done that for years.
    My knee pain has gone from 10/10 to 2/10
    I wish I knew about this 20 years ago, it would have simply changed my life. I now feel my eyes improving too.

  • http://www.victoriahealth.com/ Victoria Health

    Thank you for the feedback, Hyaluronic acid certainly is known to help cushion the joints.
    Best wishes,

  • Anne

    Hi Chris
    What product are you taking please. so many out there. Thanks

  • http://www.victoriahealth.com/ Victoria Health

    Hi Kim, almost everything we ingest does get absorbed – it is just relatively how much of an ingredient or vitamin actually reaches the bloodstream. In the case of hyaluronic acid, a massive 225mg of this nutrient is used so as to ensure that at least a small amount gets into the bloodstream where all the tissues in the body will utilise this vital nutrient.

  • http://www.victoriahealth.com/ Victoria Health

    Hi Kim, the extract below from the NIH in the US which collates all studies and summarises them.
    “HA is a safe raw material and the efficacy of oral HA in relieving knee pain was demonstrated in several clinical trials. HA as a dietary supplement exhibits mild efficacy and no side effects. By utilizing these characteristics, HA dietary supplements provide at least some possibility for the treatment and prevention of serious conditions in patients with OA exhibiting mild knee pain.”

    Best wishes,

  • Tinisha Lambeth

    Hi Shabir,

    My husband has unilateral shoulder pain when he raises his arm above his head. Would you recommend this product or VH Superior Joints?


  • http://www.victoriahealth.com/ Victoria Health

    Hi Tinisha, I have recently also had idiopathic shoulder pain and have found Superior Joints to be excellent at alleviating pain and ensuring mobility of the shoulder.
    Best wishes,