Vitamin B6 found in conventional supplements plays a crucial role in numerous life processes. The pyridoxamine form of vitamin B6, however, has been validated to protect the body’s living proteins via multiple independent mechanisms.
There are three different forms of vitamin B6 (pyridoxine, pyridoxal, pyridoxamine). All are important and can be converted in the body to the active form of B6 called PLP or P5P which the body uses in many pathways. The pyridoxamine form is considered to be the most potent anti-ageing form because of its ability to enhance glucose metabolism, quench toxic free radicals, and help block formation of advanced glycation end-products (AGEs). Glycation occurs when sugars react with the body’s proteins, resulting in the formation of non-functioning glycation end products. While glycation is a normal consequence of ageing, it is far from desirable.
Collagen accounts for about a third of our total body proteins. Glycation causes the collagen in our skin and tissues throughout our bodies to cross-link, leading to unsightly characteristics of aging both physically on the appearance of skin and the ageing of the body's glands such as the heart muscle tissue, arteries and veins and other organs.
Scientific research suggests that if you want to help protect your body against some of the effects of ageing, nutrients that help prevent the formation of AGEs may be beneficial. The latest information shows that pyridoxamine may be of significant help in preventing the formation of these ageing molecules. In fact, one prominent anti-ageing doctor described pyridoxamine as "the most potent natural substance for inhibiting AGE formation." By preventing AGE formation and working as a coenzyme in chemical reactions, pyridoxamine can support healthy nerve, eye, cardiovascular and kidney function.